Nightmare Moon, for various reasons, mainly she's more powerful Fantasy vs Sci-FI (Star Wars is kind of Science Fantasy)
Sci-fi, which has Doctor Who and Transformers, among others. Kenny McCormick vs. Master Roshi in a perv-off. Sent from the DeLorean
Roshi. You don't know the patience he has..... Mohammad Ali and Mike Tyson (at their peak) vs. The entire roster from Punch Out in individual fights
Mohammad Ali and Mike Tyson The Lone Wanderer from vault 101 (From Fallout 3) vs the Mail-man (From Fallout New vegas) in a death match.
Probably the Courier (I assume that's what you meant by 'mail-man') He has access to better Equipment and perks. British Royal Palace Guard vs US White House Marine Sentries?
Kirby. That little dude could just suck them all up (no dirty jokes please) KITT from Knight rider vs. the DMC delorean time machine from back to the future in a 1/2 mile drag race
Kitt. The DeLorean takes too long just to get up to 55! Beavis & Butt-Head Vs. Snips & Snails in a nacho eating contest
Tell me, Pennywise, you ever dance with the devil in the pale moonlight? Sting (wrestler) Vs. Eric Draven (The Crow)
Sting. Because Eric doesn't die halfway during the movie. One Black Templar (40k) vs. Fifteen Spartan II's (Halo)
The T-virus. Venom doesn't kill its host. Shizuo Heiwajima (DRRR!!) vs The Incredible Hulk (1978 TV series version)